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The following information includes only the average doses of chloramphenicol. Considering this, chloramphenicol should be administered cautiously to animals with hematopoietic dysfunction. Usual Adult Dose for Intraabdominal Infection:2 g IV every 8 hours for 7 to 14 days, depending on the nature and severity of the infectionUsual Adult Dose for Melioidosis:2 g IV every 8 hoursParenteral therapy should be continued for at least 10 days, followed by doxycycline 100 mg orally twice daily plus chloramphenicol 10 mg/kg orally (not available in the United States) four times daily plus sulfamethoxazole-trimethoprim 25 mg/kg - 5 mg/kg orally twice a day. Development of resistance to chloramphenicol can be regarded as minimal for staphylococci and many other species of bacteria. chloramphenicol may be given alone or with other medicines that are taken by mouth for eye infections. Most susceptible infectious disease organisms will respond to chloramphenicol therapy in three to five days when the recommended dosage regimen is followed. Tampoco se conoce si el chloramphenicol oft?lmico pasa a la leche materna. There is no specific information comparing use of chloramphenicol in the elderly with use in other age groups. There have been reports of aplastic anemia attributed to chloramphenicol which later terminated in leukemia. Chloramphenicol should not be used when less potentially dangerous agents would be expected to provide effective treatment. Si est? embarazada, no use el chloramphenicol oft?lmico sin antes consultar con su m?dico. Siga usando el chloramphenicol oft?lmico y consulte con su m?dico acerca de cualquier efecto secundario que usted nota. Chloramphenicol may also be effective against rickettsiae and the mycoplasma (PPLO) group of organisms. However, other USP experts still consider ophthalmic chloramphenicol valuable because of its lipid solubility and excellent corneal penetration, as well as its low ocular toxicity when compared with other antibacterials commonly used in the eye (e. In addition, there have been reports of aplastic anemia attributed to chloramphenicol which later terminated in leukemia. Chloramphenicol must not be used when less potentially dangerous agents will be effective. Chloramphenicol ophthalmic preparations are used to treat infections of the eye. Doxycycline and sulfamethoxazole-trimethoprim should be continued for 20 weeks; chloramphenicol for the first 8 weeks. Because of reported systemic toxicity, some USP medical experts recommend that ophthalmic chloramphenicol be reserved for serious ocular infections in which the etiologic organisms are resistant to all other ophthalmic antibiotics or for infections in which less toxic antibiotics are ineffective. However, with newer drugs available for bacterial infections, chloramphenicol use has decreased dramatically. Concurrent administration of chloramphenicol and primidone (or the other primary anticonvulsants) may result in accumulation of the anticonvulsant drug and clinical signs of toxicity (sedation, ataxia, prolonged anesthesia). Mantenga el chloramphenicol oft?lmico a temperatura ambiente fuera del calor y de la humedad. No se conoce si el chloramphenicol oft?lmico da?ar? al beb? nonato. After using chloramphenicol eye ointment, wipe the tip of the ointment tube with a clean tissue and keep the tube tightly closed. Laboratory studies demonstrate that it may be displaced from plasma albumin by various compounds including sulfonamides, salicylates, tetracyclines, chloramphenicol, and phenytoin. 9% sodium chloride injection, or 10% invert sugar and electrolytes injection, and with intravenous solutions containing vitamin B complex, vitamin B complex and ascorbic acid, cephalothin, cephoranide, tetracycline hydrochloride, ampicillin, methicillin, chloramphenicol, or polymyxin B sulfate. In serious ocular infections, topical chloramphenicol should be given concurrently with appropriate systemic antibacterials. If you stop using chloramphenicol too soon, your symptoms may return.



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